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-syn aggregation leads to increased iron deposition and ferroptosis in PD mice, while MT1 knockout reduces the resistance of neurons to ferroptosis by inhibiting the SIRT1/Nrf2/HO-1/GPX4 pathway and inhibiting the expression of ferritin FTH1, resulting in more ferrous ion release, which further leads to more DA neuron loss and severe dyskinesia

While the exposure from bacteriostatic water is very low, there is a theoretical risk that an infant could ingest benzyl alcohol through breast milk

Weak antioxidant defenses make the heart a target for damage in copper-deficient rats